US scientists create most comprehensive circuit diagram of mammalian brain

3D map of a cubic millimetre of mouse brain reveals half a billion synapses and 5.4km of neuronal wiring

The most comprehensive circuit diagram of neurons in a mammalian brain has been created by scientists, providing groundbreaking insights into the mystery of how the brain works.

The map is of a speck of a mouse’s visual cortex, smaller than a grain of sand, and traces the structure of 84,000 neurons linked by half a billion synapses and approximately 5.4km of neuronal wiring. The 3D reconstruction of the cubic millimetre of brain is helping uncover how the brain is organised and how different cell types work together, and could have implications for the understanding of intelligence, consciousness and neuronal conditions such as Alzheimer’s, Parkinson’s, autism and schizophrenia.

Continue reading…

About Author